neural cell adhesion molecules การใช้

• SCLC derived from neuroendocrine cells may express CD56, neural cell adhesion molecule, synaptophysin or chromogranin.
• NCCs additionally require the repression of N-cadherin, and neural cell adhesion molecule ( NCAM ).
• In addition, neural cell adhesion molecule ( NCAM ) is known to enhance Schwann cell motility " in vitro ".
• Sialic acid in the form of polysialic acid is an unusual posttranslational modification that occurs on the neural cell adhesion molecules ( NCAMs ).
• The neural cell adhesion molecule NCAM1 appears on early embryonic cells and is important in the formation of cell collectives and their boundaries at sites of morphogenesis.
• Heparin binding sequences K?AFAKLAARLYRKA, R?AFARLAARLYRRA, KHKGRDVILKKDVR, YKKIIKKL are from antithrombin III, modified antithrombin III, neural cell adhesion molecule and platelet factor 4, respectively.
• One of the most significant discoveries made in this research is that the precursor gene for the neural cell adhesion molecule gave rise in evolution to the entire molecular system of adaptive immunity.
• The encoded protein may be found in the Golgi apparatus and may be involved in the production of polysialic acid, a modulator of the adhesive properties of neural cell adhesion molecule ( NCAM1 ).
• The neural cell adhesion molecule N-CAM simultaneously combines with another N-CAM and a fibroblast growth factor receptor to stimulate the tyrosine kinase activity of that receptor to induce the growth of neurites.
• With immunohistochemistry, the chief cells located in the cell balls are positive for chromogranin, synaptophysin, neuron specific enolase, serotonin, neurofilament and Neural cell adhesion molecule; they are S-100 protein negative.
• Chronic administration of corticosteroids decreases 5-HT1A receptor binding, 5-HT2 receptor binding, serotonin levels, and expression of neural cell adhesion molecule ( a cell-surface macromolecule involved in regulating aspects of synapse stabilization ).
• Neural cell adhesion molecule ( N-CAM ) will mediate this attachment via homophilic ( N-CAM binds only to that isotope of N-CAM : A with A, B with B, never A with B ) interactions.
• Some studied have reported that neuroendocrine-related markers ( i . e . neuron-specific enolase ( NSE ), neural cell adhesion molecule ( NCAM ), chromogranin A ( CgA ), synaptophysin ), are also quite frequently expressed in a significant proportion of rhabdoid cells.
• This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP . The extracellular region contains three Ig-like domains, and nine non-Ig like domains similar to that of neural cell adhesion molecule.
• "' Figure 6-1 ( a ) . "'( Panel A ) Expression of polysialic acid form of neural cell adhesion molecule ( PSA-NCAM ) in the hippocampus of rats that were irradiated ( IR ) with 2.5 Gy of 56Fe high-energy radiation and control subjects as measured by % density / field area measured . ( Panel B ) PSA-NCAM staining in the dentate gyrus of representative irradiated ( IR ) and control ( C ) subjects at 5x magnification.